Kevin Whelan Selected Research

5-HT2A Serotonin Receptor (5 HT2A Receptor)

3/2012	Identification of fused bicyclic heterocycles as potent and selective 5-HT(2A) receptor antagonists for the treatment of insomnia.
8/2010	Synthesis and in vivo evaluation of phenethylpiperazine amides: selective 5-hydroxytryptamine(2A) receptor antagonists for the treatment of insomnia.

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Kevin Whelan Research Topics

Disease

18	Irritable Bowel Syndrome (Syndrome, Irritable Bowel) 01/2022 - 11/2011
14	Crohn Disease (Crohn's Disease) 04/2024 - 08/2007
9	Inflammatory Bowel Diseases (Inflammatory Bowel Disease) 01/2023 - 08/2007
8	Inflammation (Inflammations) 02/2024 - 08/2013
8	Diarrhea 05/2015 - 09/2002
6	Dysbiosis 01/2017 - 01/2009
5	Constipation 11/2023 - 10/2014
4	Ulcerative Colitis 04/2024 - 03/2014
4	Body Weight (Weight, Body) 01/2023 - 05/2008
4	Obesity 09/2019 - 05/2008
3	Abdominal Pain (Pain, Abdominal) 01/2019 - 11/2015
3	Flatulence 01/2019 - 12/2017
3	Epistaxis (Nosebleed) 01/2017 - 01/2013
3	Neoplasms (Cancer) 08/2015 - 12/2006
3	Autoimmune Diseases (Autoimmune Disease) 12/2014 - 07/2012
3	Sleep Initiation and Maintenance Disorders (Insomnia) 03/2012 - 03/2010
2	Sarcopenia 01/2023 - 01/2021
2	Phenylketonurias (Phenylketonuria) 01/2022 - 01/2021
2	Celiac Disease (Celiac Sprue) 10/2021 - 01/2018
2	Respiratory Insufficiency (Respiratory Failure) 01/2021 - 01/2019
2	Pouchitis 10/2020 - 03/2014
2	Pain (Aches) 12/2017 - 01/2015
2	Iron Deficiencies 01/2017 - 01/2013
2	Hereditary Hemorrhagic Telangiectasia 01/2017 - 01/2013
2	Infections 08/2015 - 03/2010
2	Weight Loss (Weight Reduction) 06/2015 - 01/2013
1	Liver Diseases (Liver Disease) 11/2023
1	Sleep Wake Disorders 01/2023
1	Tremor (Tremors) 01/2023
1	Hypokinesia (Bradykinesia) 01/2023
1	Anorexia Nervosa 01/2023
1	Olfaction Disorders (Cacosmia) 01/2023
1	Biliary Atresia 01/2022
1	Cholestasis 01/2022
1	Colitis 10/2021
1	Frailty 01/2021
1	Cystic Fibrosis (Mucoviscidosis) 01/2019
1	Pelvic Neoplasms 09/2017
1	Gastrointestinal Diseases (Functional Gastrointestinal Disorders) 03/2017
1	Hypersensitivity (Allergy) 01/2017
1	Osteoarthritis 01/2015

Drug/Important Bio-Agent (IBA)

16	PrebioticsIBA 01/2023 - 08/2007
8	Phenobarbital (Luminal)FDA Link 01/2022 - 11/2011
7	OligosaccharidesIBA 01/2022 - 07/2011
6	Fructans (Levans)IBA 12/2021 - 11/2015
6	CarbohydratesIBA 12/2017 - 08/2012
5	MonosaccharidesIBA 01/2022 - 05/2016
5	DisaccharidesIBA 01/2022 - 05/2016
5	Inulin FDA Link 01/2019 - 08/2013
4	Leukocyte L1 Antigen Complex (Calgranulin)IBA 01/2023 - 10/2014
4	Proteins (Proteins, Gene)FDA Link 01/2023 - 01/2021
4	IronIBA 01/2018 - 01/2013
4	Anti-Bacterial Agents (Antibiotics)IBA 05/2015 - 03/2008
3	VitaminsIBA 11/2023 - 08/2015
3	Dietary Fiber FDA Link 10/2021 - 03/2014
3	oligofructoseIBA 11/2015 - 08/2013
2	Phenylalanine (L-Phenylalanine)FDA Link 01/2022 - 01/2021
2	Glutens (Glutelin)IBA 01/2022 - 09/2018
2	16S Ribosomal RNAIBA 10/2021 - 01/2017
2	Volatile Fatty AcidsIBA 10/2021 - 01/2009
2	Food Additives (Food Additive)IBA 06/2021 - 09/2020
2	5-HT2A Serotonin Receptor (5 HT2A Receptor)IBA 03/2012 - 08/2010
2	Serotonin (5 Hydroxytryptamine)IBA 08/2010 - 05/2008
1	Sweetening Agents (Sweeteners)IBA 02/2024
1	Magnesium Oxide (Magnesia)FDA Link 11/2023
1	MineralsIBA 11/2023
1	Triglycerides (Triacylglycerol)IBA 11/2023
1	CytokinesIBA 01/2023
1	Dietary ProteinsIBA 01/2023
1	ChemokinesIBA 01/2023
1	Tryptophan (L-Tryptophan)FDA Link 01/2023
1	Proton Pump InhibitorsIBA 01/2023
1	polyolIBA 01/2022
1	BilirubinIBA 01/2022
1	PhenolsIBA 10/2021
1	Sorbitol (Yal)FDA Link 10/2021
1	Drinking WaterIBA 09/2020
1	Polysorbates (PSML)FDA Link 09/2020
1	Gum Arabic (Acacia, Gum)FDA Link 09/2020
1	LecithinsIBA 09/2020
1	PolyphenolsIBA 09/2019
1	EnzymesIBA 01/2019
1	CalciumIBA 01/2018
1	Volatile Organic CompoundsIBA 01/2018
1	Glucose (Dextrose)FDA LinkGeneric 12/2017
1	Bile Acids and Salts (Bile Acids)IBA 05/2017
1	T-Cell Antigen Receptors (T-Cell Receptor)IBA 08/2015
1	Azathioprine (Imuran)FDA LinkGeneric 08/2015
1	Therapeutic UsesIBA 06/2015
1	LigandsIBA 01/2015

Therapy/Procedure

11	Enteral Nutrition (Feeding, Tube) 05/2015 - 09/2002
9	Therapeutics 04/2024 - 08/2013
9	Diet Therapy (Therapy, Diet) 12/2021 - 08/2012
2	Gluten-Free Diet 10/2021 - 01/2018
2	Extracorporeal Membrane Oxygenation 01/2021 - 01/2019
2	Radiotherapy 09/2017 - 12/2006
1	Precision Medicine 04/2024
1	Restorative Proctocolectomy 10/2020
1	Enzyme Replacement Therapy 01/2019
1	Gastric Bypass (Roux-en-Y Gastric Bypass) 06/2015